Which vitamin is routinely given to newborns at birth to prevent hemorrhagic disease?

Prepare for the Foundation Year Pharmacy Exam. Study with flashcards and multiple-choice questions. Each question comes with hints and explanations. Ensure your readiness for the exam!

Multiple Choice

Which vitamin is routinely given to newborns at birth to prevent hemorrhagic disease?

Explanation:
Vitamin K is given at birth to prevent hemorrhagic disease because newborns have very low stores of this vitamin and their gut is initially sterile, so they cannot rapidly synthesize it. Vitamin K is essential for activating clotting factors II, VII, IX, and X, as well as proteins C and S. Without adequate vitamin K, the coagulation cascade is impaired, increasing the risk of serious bleeding, including intracranial hemorrhage. Breast milk contains only small amounts of vitamin K, and the gut needs time to establish bacteria that produce it, so a prophylactic dose at birth rapidly replenishes stores and prevents deficiency bleeding. The other vitamins listed do not prevent this neonatal bleeding risk.

Vitamin K is given at birth to prevent hemorrhagic disease because newborns have very low stores of this vitamin and their gut is initially sterile, so they cannot rapidly synthesize it. Vitamin K is essential for activating clotting factors II, VII, IX, and X, as well as proteins C and S. Without adequate vitamin K, the coagulation cascade is impaired, increasing the risk of serious bleeding, including intracranial hemorrhage. Breast milk contains only small amounts of vitamin K, and the gut needs time to establish bacteria that produce it, so a prophylactic dose at birth rapidly replenishes stores and prevents deficiency bleeding. The other vitamins listed do not prevent this neonatal bleeding risk.

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